Review



ye6144 in dmso  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 92
      Buy from Supplier

    Structured Review

    MedChemExpress ye6144 in dmso
    A) Experimental design for testing the IRF5 inhibitor <t>YE6144</t> on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.
    Ye6144 In Dmso, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ye6144 in dmso/product/MedChemExpress
    Average 92 stars, based on 1 article reviews
    ye6144 in dmso - by Bioz Stars, 2026-02
    92/100 stars

    Images

    1) Product Images from "Uncovering immune characteristics of neurons in the context of multiple sclerosis and experimental autoimmune encephalomyelitis"

    Article Title: Uncovering immune characteristics of neurons in the context of multiple sclerosis and experimental autoimmune encephalomyelitis

    Journal: bioRxiv

    doi: 10.1101/2024.08.19.608118

    A) Experimental design for testing the IRF5 inhibitor YE6144 on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.
    Figure Legend Snippet: A) Experimental design for testing the IRF5 inhibitor YE6144 on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.

    Techniques Used: Expressing, In Vitro, Cell Culture, Control, Comparison, RNA Sequencing Assay



    Similar Products

    ye6144 in dmso  (MedChemExpress)
    92
    MedChemExpress ye6144 in dmso
    A) Experimental design for testing the IRF5 inhibitor <t>YE6144</t> on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.
    Ye6144 In Dmso, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ye6144 in dmso/product/MedChemExpress
    Average 92 stars, based on 1 article reviews
    ye6144 in dmso - by Bioz Stars, 2026-02
    92/100 stars
    		  Buy from Supplier

    Image Search Results


    A) Experimental design for testing the IRF5 inhibitor YE6144 on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.

    Journal: bioRxiv

    Article Title: Uncovering immune characteristics of neurons in the context of multiple sclerosis and experimental autoimmune encephalomyelitis

    doi: 10.1101/2024.08.19.608118

    Figure Lengend Snippet: A) Experimental design for testing the IRF5 inhibitor YE6144 on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.

    Article Snippet: Cells were maintained in Neurobasal for 7 days, at which point a half media swap was conducted with either control media or stimulated PBMC-CM, containing DMSO or a final concentration of 1 uM of YE6144 in DMSO (MedChem Express, Cat. No.: HY-150095).

    Techniques: Expressing, In Vitro, Cell Culture, Control, Comparison, RNA Sequencing Assay